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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
9.39
Human Site:
S342
Identified Species:
18.79
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S342
M
G
L
E
E
L
Q
S
Q
F
G
L
K
G
F
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S344
M
G
L
E
E
L
Q
S
Q
F
G
L
K
G
F
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
L314
Q
L
Q
S
N
F
S
L
E
I
N
G
K
P
F
Dog
Lupus familis
XP_546737
807
92419
S370
M
G
L
K
E
L
Q
S
K
F
S
L
K
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
E328
M
D
L
M
E
L
Q
E
R
F
G
L
K
G
F
Rat
Rattus norvegicus
P0C1T0
774
89178
E337
M
G
L
E
E
L
Q
E
R
F
G
L
K
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
L312
E
L
Q
E
K
F
A
L
N
V
K
H
S
E
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
Q318
M
T
L
R
E
A
Q
Q
T
F
N
L
N
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
E415
Y
R
K
M
L
L
P
E
L
Q
E
L
V
P
E
Honey Bee
Apis mellifera
XP_392502
776
89056
L342
A
I
Y
R
K
L
T
L
R
E
L
Q
R
E
I
Nematode Worm
Caenorhab. elegans
O16796
848
97043
Y412
K
R
Q
I
Q
D
L
Y
N
L
L
P
Q
V
D
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
L330
N
P
T
T
L
T
G
L
M
Q
D
Y
P
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
13.3
80
N.A.
73.3
86.6
N.A.
N.A.
13.3
N.A.
53.3
N.A.
13.3
6.6
0
0
P-Site Similarity:
100
100
20
93.3
N.A.
80
93.3
N.A.
N.A.
20
N.A.
53.3
N.A.
13.3
26.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
9
% D
% Glu:
9
0
0
34
50
0
0
25
9
9
9
0
0
17
9
% E
% Phe:
0
0
0
0
0
17
0
0
0
50
0
0
0
0
67
% F
% Gly:
0
34
0
0
0
0
9
0
0
0
34
9
0
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
9
0
9
9
17
0
0
0
9
0
9
0
50
0
0
% K
% Leu:
0
17
50
0
17
59
9
34
9
9
17
59
0
0
0
% L
% Met:
50
0
0
17
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
9
0
0
0
17
0
17
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
9
0
0
0
0
9
9
17
0
% P
% Gln:
9
0
25
0
9
0
50
9
17
17
0
9
9
9
0
% Q
% Arg:
0
17
0
17
0
0
0
0
25
0
0
0
9
0
0
% R
% Ser:
0
0
0
9
0
0
9
25
0
0
9
0
9
0
0
% S
% Thr:
0
9
9
9
0
9
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _